Обязанности и достижения:
Руководство доклиническими тестами препаратов и моделирование в животных различных заболеваний
Публикации:
Grigoryev DN, Ma S-F, Ye SQ, Irizarry RA, Quackenbush J, and Garcia JGN (2004) Orthologous gene expression profiling in multi-species models: search for candidate genes. Genome Biology 5 (5):R34
Jacobson JR, Barnard JW, Grigoryev DN, Ma S-F, Tuder RM, and Garcia JGN (2005) Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol 288 (6):L1026-32
Grigoryev DN, Ma S-F, Ye SQ, Simon B, and Garcia JGN (2005) In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip technology. BMC Genomics, 6 (1):62
Grigoryev DN, Ma S-F, Taylor AD, Nonas S, Sammani S, Ye SQ, Garcia JGN (2005) Bioinformatic identification of novel early stress response genes in rodent models of lung injury. Am J Physiol Lung Cell Mol Physiol, 289 (3):L468-77
Li J, Grigoryev DN, Ye SQ, Thorne L, Schwartz AR, Smith PL, O'donnell CP, Polotsky VY (2005) Chronic intermittent hypoxia up-regulates genes of lipid biosynthesis in obese mice. J Appl Physiol 99 (5):1643
Nonas SA, Moreno Vinasco L, Ma S-F, Jacobson JR, Desai AA, Dudek S, Flores C, Hassoun PM, Sam L, Ye SQ, Moitra J, Barnard J, Grigoryev DN, Lussier YA, Garcia JG (2007) Use of consomic rats for genomic insights into ventilator-associated lung injury. Am J Physiol Lung Cell Mol Physiol 293 (2):L292-302
Papaiahgari S, Yerrapureddy A, Reddy SR, Reddy NM, Dodd-O JM, Crow MT, Grigoryev DN, Barnes K, Tuder RM, Yamamoto M, Kensler TW, Biswal S, Mitzner W, Hassoun PM, Reddy SP (2007) Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. Am J Respir Crit Care Med 176 (12):1222-35
Liu M, Chien CC, Grigoryev DN, Gandolfo MT, Colvin RB, Rabb H (2009) Effect of T cells on vascular permeability in early ischemic acute kidney injury in mice. Microvasc Res 77 (3):340-7
Liu M, Grigoryev DN, Crow MT, Haas M, Yamamoto M, Reddy SP, Rabb H (2009) Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice. Kidney Int 76 (3):277-85
Reinke C, Bevans-Fonti S, Grigoryev DN, Drager LF, Myers AS, Wise RA, Schwartz AR, Mitzner W, Polotsky VY (2011) Chronic intermittent hypoxia increases alveolar surface area in adult mice. Am J Physiol Lung Cell Mol Physiol 300 (2):L266-73